Jobbeschreibung
Your university hospital in the heart of Munich
We are the Klinikum rechts der Isar (MRI) of the Technical University of Munich (TUM) and a reliable employer for around 6,600 employees. As a university hospital, we are dedicated not only to patient care but also to research and teaching - in line with our mission statement "Knowledge creates healing" and enjoy an excellent reputation both nationally and internationally. 160 different professional groups work hand in hand to provide our patients with optimal treatment.
Bioinformatician (m/f/d)
Full- or part-time | temporary (24 month) | Institute of Human Genetics
The Institute of Human Genetics is at the forefront of genomic research and diagnostics, integrating new omics technologies into routine diagnostics. Operating within an ISO15189 accredited framework, we uphold the highest standards of quality and accuracy while pioneering and integrating cutting edge omics technologies. Moreover, our group actively participates in leading consortia such as the 1000 Bavarian Genomes Project and the DZHKomics resource and collaborates closely with the German Human Genome-Phenome Archive (GHGA) to facilitate genetic data accessibility for secondary use under the new German Law on Genomic Medicine (Modellvorhaben nach § 64e SGB V).
- Your primary task will be to maintain and enhance the clinical expert system (EVAdb) and NGS analysis platform
- Ensure the timely and accurate analysis of routine NGS samples for clinical diagnostics for patients counseled at the MVZ
- Implement, validate, and integrate new features into the pipeline infrastructure
- Continuously improve and optimize pipeline workflows
- Assist in transitioning analysis workflows and systems to a cloud-based infrastructure
- You will have the opportunity to develop an own research focus related to developing and improving cutting edge molecular genetic diagnostics
- Minimum of a Master's degree (MSc) in Bioinformatics, Informatics, Mathematics, Biology, Medicine experience in developing, deploying, and managing NGS pipelines, e.g. Nextflow or Snakemake
- Proficiency in running and building DNA, RNA and other omics data analysis pipelines including QC steps
- Experience with relational databases (MySQL / PostgreSQL) and programming languages such as Python and R
- Fluency in English (e.g. min C1 level)
- IT administration skills, including Linux administration, security measurements, and familiarity with the administration of Apache and SQL services are beneficial
- Familiarity with cloud-based systems and dockerization of workflows and applications are an added bonus
- Preference given to candidates with expertise in NGS diagnostics, integration of the processes in a laboratory management system (LIMS) and familiarity with accredited quality management procedures.
- Initially a fixed-term employment contract with the possibility of extension
- EGYM well pass, corporate benefits and discounts (e. g. Käfer), cafeteria, sports and cultural offers, company bike
- Free use of the library through a branch of the Munich City Library located in the building
- Working in the heart of Munich at Max-Weber-Platz with very good accessibility by public transport such as the subway, S-Bahn or tram
- Company pension plan through the Federal and State Pension Institute (VBL)
- Self-realization through a varied and technically demanding job with interdisciplinary cooperation between various departments of the MRI