PhD Position for QM / MM Simulations of Membrane Proteins

Forschungszentrum Jülich GmbH

  • Jülich
  • Veröffentlicht am: 23. Januar 2025
Jobbeschreibung

Conducting research for a changing society: This is what drives us at Forschungs­zentrum Jülich. As a member of the Helm­holtz Asso­ciation, we aim to tackle the grand societal challenges of our time and conduct research into the possi­bilities of a digitized society, a climate-friendly energy system, and a resource-efficient economy. Work together with around 7,400 employees in one of Europe's biggest research centers and help us to shape change!

The Institute of Neuroscience and Medicine – Computational Biomedicine (INM-9) at Forschungszentrum Jülich – www.fz-juelich.de/en/inm/inm-9 – uses and develops high-performance computing-based multiscale approaches to investigate key molecular events for neuronal function and dysfunction. INM-9 is also part of relevant European initiatives like the joint doctorate program STIMULATE – stimulate-ejd.eu/ – and the Center of Excellence BioExcel – bioexcel.eu/ – to support the use of high-performance computing and high-throughput computing in biomolecular research. With the advent of exascale HPC platforms in few years, multiscale simulations, such as quantum mechanical / molecular mechanics (QM / MM) simulations, will be able to describe a large variety of biological processes at high accuracy. The successful candidate for this PhD position will apply a novel, massively parallel QM / MM approach, developed in collaboration with a European consortium (Bolnykh et al., JCTC, 2019), to investigate the function of ion channels in membrane protein systems.

We are offering a

PhD Position for QM / MM Simulations of Membrane Proteins


  • Modeling and characterization at molecular level of selected biological processes by performing classical molecular dynamics and QM / MM simulations and employing enhanced sampling methods based on the recently developed QM / MM interfaces
  • Writing and submitting computational proposals to obtain the computational resources required to accomplish the project
  • Engaging in the international simulation community
  • Publishing the results of this project in international journals and presenting them at international meetings and conferences

  • Excellent university (master's) degree in physics, chemistry, bioinformatics, or a related field
  • Experience in theoretical (bio-)chemistry and/or in physics
  • Basic knowledge of computational biology techniques as well as the Unix operative system is highly appreciated
  • Good command of spoken and written English
  • Communication and teamwork skills

We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We offer ideal conditions for you to complete your doctoral degree:

  • Outstanding scientific and technical infrastructure
  • A highly motivated group as well as an international and interdisciplinary working environment at one of Europe's largest research establishments
  • Chance of participating in (international) conferences and project meetings
  • Continuous scientific mentoring by your scientific advisor
  • Doctoral degree conferred by RWTH Aachen University
  • Part-time position with 19.5 hours per week and flexible working hours
  • 30 days of annual leave (depending on agreed working time arrangements) and provision for days off between public holidays and weekends (e.g., between Christmas and New Year)
  • Further development of your personal strengths, e.g., through an extensive range of training courses; a structured program of continuing education and networking opportunities specifically for doctoral researchers via JuDocS, the Jülich Center for Doctoral Researchers and Supervisors: fz-juelich.de/en/judocs

In addition to exciting tasks and a collaborative working atmosphere at Jülich, we have a lot more to offer: go.fzj.de/benefits.

The position is for a fixed term of three years. Pay will be in line with 70% of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund) and additionally 60% of a monthly salary as special payment (“Christmas bonus”). Pay higher than the basic pay may be possible. The monthly salaries in euros can be found on page 66 of the PDF download: go.fzj.de/bmi.tvoed. Further information on doctoral degrees at Forschungszentrum Jülich, including our other locations, is available at: fz-juelich.de/gp/Careers_Docs.

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