Chemical Technical Assistant (m/w/d)

Ariceum Therapeutics GmbH

  • Berlin
  • Post Date: 26. November 2024
Job Description

Ariceum Therapeutics GmbH is a rapidly growing clinical-stage company focused on developing next-generation radiopharmaceutical cancer therapeutics and diagnostics. Our pipeline includes Lutetium-177 Satoreotide (SSO110), paired with Gallium-68 Satoreotide (SS0120), for the combined diagnosis and targeted radionuclide treatment of neuroendocrine cancers. Additionally, our novel therapeutic product, Iodine-123 ATT001, a radiolabeled PARP inhibitor, is in a Phase 1 clinical trial for recurrent glioblastoma. Headquartered in Berlin, we have subsidiaries in Germany, Switzerland, and Australia, with team members across Europe, the USA, and Australia.

We are seeking a Chemical Technical Assistant to join our radiopharmaceutical development & CMC team.

Purpose of the position:

  • Support development programs and assist the Head of Laboratory in advancing the company's methods and activities.
  • Undertake, monitor, produce, and coordinate technical studies, including process optimization.
  • Oversee equipment and premises relevant to assigned activities.
  • Contribute to clinical study trial activities.

  • Planning, controlling, coordination, monitoring and implementation of development-relevant processes, manufacturing and analytical procedures in radiopharmaceutical development.
  • Performing radioactive and non-radioactive syntheses and analyses, including preliminary and subsequent work and documentation.
  • Document development, testing, and validation processes in compliance with pharmaceutical manufacturing authorizations.
  • Preparation, planning and execution of all production-related and documentary processes.
  • Support in the installation and qualification activities to remodel the laboratory areas.
  • Compiling and assembling documentation in the area of responsibility.
  • Involvement in the transfer of development results into clinical trial partners.
  • Compiling supplies for delivery to collaboration partners.

Ideal: Degree/qualification and significant industrial experience in radiopharmaceutical development and handling of radioactive substances with strong analytical background.

Minimum: Experience in pharmaceutical and analytical development in early or late-stage drug substances and products with adequate educational training.

Languages: Fluent English is required; German is a plus.

Required Competencies:

  • Instrument-based analytics
  • Chromatography e.g. High-performance liquid chromatography, Thin-layer chromatography
  • Spectroscopy e.g. Ultraviolet–visible spectroscopy
  • Spectrometry e.g. mass spectrometry
  • Other e.g. pH, conductivity, water-content, oxygen-content
  • Capabilities for operation and user programming of computer-controlled systems
  • Structured and highly problem-solving oriented way of thinking

  • Permanent employment with long-term career prospects.
  • Flexible teamwork with partial remote working option.
  • A welcoming, inclusive and innovative work environment that values open communication and collaboration.
  • Opportunities for continuous professional development and growth.
  • Social benefits, including a public transport job ticket (Job ticket).
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